By Dr. Youngran ParkDNA damage response in eutopic endometria of endometriosis patients
By Dr. Youngran Park
The DNA damage response (DDR) is a network of cellular pathways that sense, signal, and repair the lesions occurring in DNA. Surveillance proteins that monitor DNA integrity activate the DNA repair pathways in response to DNA damage and try to prevent the generation of potentially deleterious mutations. Endometriosis is an estrogen-dependent…
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By Kasthuri NairO6-Methylguanine-DNA Methyltransferase Plays a Role in Endometriosis Development
By Kasthuri Nair
Shchegolev et al. recently published a paper in Bulletin of Experimental Biology and Medicine that explores the localization and behavior of O6-methylguanine-DNA methyltransferase, otherwise known as MGMT, a protein that repairs DNA and could potentially possess therapeutic properties. Their paper…
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